Dr. Trayanova is the Murray B. Sachs Professor in the Department of Biomedical Engineering and Institute for Computational Medicine at Johns Hopkins University. The research in Dr. Trayanova’s Computational Cardiology Lab centers on understanding the normal and pathological electrophysiological and electromechanical behavior of the heart using multiscale simulation approaches that include biophysically detailed representations of cellular and subcellular processes and image-based descriptions of the geometry and structure of the heart. Research projects focus on the mechanisms for cardiac arrhythmogenesis and cardiac electromechanical interactions. Importantly, a large number of projects are devoted to the improvement of the clinical therapies of defibrillation, infarct-related ventricular ablation, and cardiac resynchronization therapy using a personalized approach.