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Program

THURSDAY JANUARY 14, 2010
REGISTRATION: 8:00 AM - 12:00 Noon
Exhibit Floor 11:00 AM - 5:00 PM
All Lectures are followed by a 5-minute question and answer session.
THURSDAY JANUARY 14, 2010
Afternoon Scientific Session
1:00 PM-6:00 PM
1:00 - 1:10 PM

Introduction and Overview of the Symposium
Jeremy Ruskin, MD
1:15 - 1:35 PM The History of Atrial Fibrillation: A Century of Progress
Eric Prystowsky, MD
1:40 - 2:00 PM New Observations on Mechanisms Underlying the Transition from Organization to Fractionation of Atrial Electrical Activity During AF
Jose Jalife, MD
2:05 - 2:25 PM Basic Mechanisms by Which Exercise Training Promotes AF
Stanley Nattel, MD
2:30 - 2:50 PM Atrial Fibrillation in Competitive Athletes - Prevalence, Pathophysiology and Management
Riccardo Cappato, MD
2:55 - 3:15 PM Determinants of Atrial Thrombosis in Experimental AF - Arrhythmia vs. Substrate
Stanley Nattel, MD
3:20 - 3:50 PM Coffee Break and Exhibits
3:50 - 4:10 PM Role of Inflammation in the Pathogenesis of AF
Shih-Ann Chen, MD
4:15 - 4:35 PM Management of Asymptomatic AF in Young, Middle-Aged and Elderly Patients
A. John Camm, MD
4:40 - 5:00 PM Update on Indications, Results and Future Directions of Surgery for AF
Ralph Damiano, Jr., MD
5:05 - 6:00 PM Difficult Cases in AF Management (Antiarrhythmic Drugs, Anticoagulation, and Clinical Decision Making)
Panel and Audience Discussion

Moderator: Jeremy Ruskin, MD
Panel: A. John Camm, MD, Riccardo Cappato, MD, Peter Kowey, MD, Eric Prystowsky, MD and Albert Waldo, MD
6:00 PM Adjourn
FRIDAY JANUARY 15, 2010
Morning Scientific Session
7:00 AM - 12:10 PM
6:00 - 7:00 AM Continental Breakfast
7:00 - 10:00 AM Satellite Case Transmissions: Catheter Ablation for Atrial Fibrillation
Moderator: Jeremy Ruskin, MD
Panel: Pierre Jais, MD, Shih-Ann Chen, MD, Francis Marchlinski, MD, and David Wilber, MD

Massachusetts General Hospital, Boston, Massachusetts
Moussa Mansour, MD, Kevin Heist, MD, PhD and Conor Barrett, MD

Mayo Clinic, Rochester, Minnesota
Douglas Packer, MD and Samuel Asirvatham, MD
10:00 - 10:30 AM Coffee Break and Exhibits
10:30 - 10:50 AM Emerging Role of Transcription Factors in the Development of AF:
Insights from Genetic Studies
Patrick Ellinor, MD, PhD
10:55 - 11:15 AM Epidemiology and Predicting Risk for Atrial Fibrillation
Emelia Benjamin, MD
11:20 - 11:40 AM Classification of Symptoms in AF - Rationale, Methods and Limitations
Jeremy Ruskin, MD
11:45 - 12:05 PM The Promise and Peril of New Antiarrhythmic Drug Development: What Is the New Path Forward After ATHENA?
Peter Kowey, MD
12:10 - 1:00 PM Lunch and Exhibits
FRIDAY JANUARY 15, 2010
Afternoon Scientific Session
1:00 PM - 6:10 PM
1:00 - 2:55 PM MiniSymposium on Stroke Prevention in Atrial Fibrillation: A New Era of Drugs and Devices
Moderator: Daniel Singer, MD

Overview of Long-term Anticoagulation for AF - Where We Stand in 2010 (20 min)
Daniel Singer, MD

Completed Phase III Trials of Dabigatran and Other Agents RE-LY,
ACTIVE A, W & I) - Design, Results and Clinical Implications (20 min)
Stuart Connolly, MD

The Significance of Atrial Arrhythmias Detected by Implanted Devices (15 min)
Albert Waldo, MD

Left Atrial Appendage Exclusion Devices: Current Clinical Trials (20 min)
Zoltan Turi, MD

Panel and Audience Discussion: (40 min)
What Will Be the Role for Dabigatran and Other Novel Agents vs.
Warfarin Going Forward?
Will LAA Occlusion/Exclusion Replace Long-Term Anticoagulation
to Prevent Stroke in AF?

Moderator: Hasan Garan, MD
Panel: Stuart Connolly, MD, Vivek Reddy, MD, Daniel Singer, MD, Zoltan Turi, MD, and Albert Waldo, MD
2:55 - 3:25 PM Coffee Break and Exhibits
3:25 - 4:05 PM Regulatory Issues in AF Ablation
Moderator: Hugh Calkins, MD

FDA Perspective on AF Ablation Studies - A New Regulatory Landscape (10 min)
Randall Brockman, MD

Sponsor vs. Single-Site Investigator Initiated Clinical Studies to Support a Market Application for AF Devices (10 min)
Jun Dong, MD

Audience Question and Answer Session (20 min)
4:05 - 4:25 PM Current Status of Clinical Trials of AF Ablation Devices Seeking FDA Approval
Hugh Calkins, MD
4:30 - 4:50 PM New Observations from the Second Worldwide Survey on AF Ablation
Riccardo Cappato, MD
4:55 - 5:15 PM Long-Term Outcome and Risks of Catheter Ablation for Atrial Fibrillation
Carlo Pappone, MD, PhD
5:20 - 5:40 PM Progression of Atrial Fibrillation: Impact on Ablation Strategies and Outcomes
David Wilber, MD
5:45 - 6:05 PM Monitoring after AF Ablation: Implications for Long-term Anticoagulation
Hans Kottkamp, MD
6:10 PM Adjourn
SATURDAY JANUARY 16, 2010
Morning Scientific Session
7:30 AM - 12:30 PM
6:30 - 7:30 AM Continental Breakfast
7:30 - 8:30 AM Panel: Practical Approaches to Catheter Ablation (all talks 15 min)

Moderator: Douglas Packer, MD
BOX Isolation for AF - Rationale, Technique and Outcomes - Koichiro Kumagai, MD

Mitral Isthmus Ablation - A New Approach
- Karl-Heinz Kuck, MD

Difficult Transseptals & SVC Isolation - Vivek Reddy, MD

Coronary Sinus and Persistent Left SVC Isolation - David Keane, MD, PhD
8:35 - 8:55 AM The Use of Multielectrode Catheters for Electroanatomic Mapping
During Catheter Ablation of Atrial Fibrillation
Moussa Mansour, MD
9:00 - 9:20 AM 4 and 5-D Image-Integrated Mapping for Atrial Fibrillation Ablation
Douglas Packer, MD
9:25 - 9:45 AM Endpoints for Catheter Ablation of AF Revisited
Francis Marchlinski, MD
9:50 - 10:20 AM Coffee Break and Exhibits
10:20 - 11:00 AM Debate: Termination of AF is a Useful Procedural Endpoint and Predictor of Outcome for Catheter Ablation of Persistent AF (all talks 20 min)

Moderator: Hans Kottkamp, MD
Pro: Pierre Jais, MD
Con: Andrea Natale, MD
11:05 - 12:05 PM MiniSymposium on Contact Force Sensing (all talks 15 min)

Moderator: David Keane, MD, PhD

Clinical Feasibility Study of Contact Force Sensing - Karl-Heinz Kuck, MD

Control of RF Lesion Size Using a New Contact Force Sensor - Hiroshi Nakagawa, MD, PhD

Observations on a New Capacitance Force Sensor - Gerhard Hindricks, MD

Force-Time Integral and Perforating Force Threshold: New Parameters for Improving the Efficacy and Safety of Catheter Ablation - Dipen Shah, MD
12:10 - 12:30 AM Atrial Flutter After AF Ablation - Incidence, Predictors, Mechanisms and Management
Pierre Jais, MD
12:35 - 1:20 PM Lunch and Exhibits
SATURDAY JANUARY 16, 2010
Afternoon Scientific Session
1:20 PM - 5:45 PM
1:20 - 2:00 PM Debate: Entrainment Mapping is Preferable to 3-D Activation Sequence Mapping for Ablation of Left Atrial Tachycardias After PVI (all talks 20 min)

Moderator: Frank Marchlinski, MD
Pro: Gerhard Hindricks, MD
Con: Hiroshi Nakagawa, MD, PhD
2:10 - 2:30 PM Interaction of Central and Intrinsic Cardiac Autonomic Nervous System in AF
Warren Jackman, MD
2:35 - 3:35 PM Optimizing the Safety of Catheter Ablation for AF (all talks 10 min)
Moderator: David Wilber, MD

Pulmonary Vein Stenosis - Douglas Packer, MD
Esophageal Injury - Conor Barrett, MD
Safety of Uninterrupted Warfarin Use in AF Ablation - Andrea Natale, MD
Other Short and Long Term Complications of AF Ablation - Andre d'Avila, MD, PhD

Panel and Audience Discussion (20 min)
Panel: Andre d'Avila, MD, PhD, Conor Barrett, MD, Koichiro Kumagai, MD, Andrea Natale, MD, Douglas Packer, MD and Carlo Pappone, MD, PhD
3:40 - 4:00 PM Balloon-Based Systems for AF Ablation - Outcomes and Complications
Vivek Reddy, MD
4:05 - 4:25 PM Current Status of Remote and Robotic Navigation for AF Ablation
Andrea Natale, MD
4:30 - 4:45 PM Ice Cream Break
4:45 - 5:45 PM Interesting and Challenging Cases in AF Management
Panel and Audience Discussion

Moderator: Vivek Reddy, MD
Panel: Pierre Jais, MD
Karl Heinz-Kuck, MD, Moussa Mansour, MD, Francis Marchlinski, MD and David Wilber, MD
5:45 PM Adjourn


 
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