31st Annual International AF Symposium™
Preliminary Scientific Program 2026
This intensive three-day symposium brings together the world's leading medical scientists to share the most recent advances
in the field of atrial fibrillation in a highly interactive environment.
THURSDAY, FEBRUARY 5, 2026
7:00-7:30 AM Welcome and Introduction
7:30-8:30 AM
New Trends in Prediction and Risk Factor Modification for AF
All lectures 7 minutes. Panel and Audience Discussion 25 minutes.
Predicting Risk for Atrial Fibrillation in the Era of Artificial Intelligence
Impact of Diet on Risk of AF and AF Ablation Outcomes
Role of GLP-1 RA, SGLT2i, and Metformin on AF and AF Ablation Outcomes
Current Status and Future Role of Genetics in the Management of AF
Integrating Wearables into Clinical Trials and Electrophysiology Practice
Panel and Audience Discussion (25 minutes)
8:30-9:30 AM
Spotlight Session – New and Emerging Technologies in EP
All lectures 5 minutes.
Image-Guided Cardioneuroablation Planning Using ADAS 3D
Coherent Sine Burst Electroportaion (CSE) Ablation System US IDE Study for Patients with Atrial Fibrillation
First Clinical Experience with HOTWIRET: A Sheath Agnostic Transseptal Access System featuring an Intelligent Impedance-sensing Algorithm
PFAnalyzer: Electrogram-guided Pulsed Field Ablation
CONFORM Trial Update featuring AcuFORM Experience
Non-invasive Global Mapping to Guide Personalized AF Therapy and Catheter Ablation
Real-Time Tissue Assessment in Stunned Myocardium to Predict Recurrence
A Practical Guide to AI in EP Remote Monitoring: Workflows, Evidence, and Impact
Non-Invasive Mapping of AF Drivers to Guide Comprehensive Ablation Strategies
Expanding Possibilities: The Versatility of
AF-Xplorer II
9:30-10:00 AM Break
10 AM-12:30 PM
Case Transmissions Session 1
12:30-1:30 PM Lunch
1:30-2:30 PM
Case Transmissions Session 2
2:30-3:30 PM
Stroke Risk Management in Atrial Fibrillation Session I
All lectures 7 minutes. Panel and Audience Discussion 25 minutes.
Factor XI and XIa Inhibition for Stroke Prevention in AF: OCEANIC-AF, AZALEA, and Other Studies
Management of Device-Detected AF: Will ARTESIA and NOAH-AFNET 6 Change Current Guidelines?
LAA Closure in Patients with Prior Hemorrhagic or Anticoagulant-Resistant Ischemic Strokes - Update from Clinical Trials and Registries
LAA Closure Compared to Medical Therapy in Patients with AF (CLOSURE-AF Trial)
Optimal Anticoagulation and Follow-up Strategies after LAA Closure
Panel and Audience Discussion (25 minutes) – All Faculty
THURSDAY CONTINUES >>>
THURSDAY CONTINUED
3:30-4:30 PM
Stroke Risk Management in Atrial Fibrillation Session II
Supported by an Educational Grant from Boston Scientific
All lectures 7 minutes. Panel and Audience Discussion 25 minutes.
Patient Selection for Concomitant PVI and LAA Closure - Applying OPTION to Clinical Practice
Discontinuation of Anticoagulation After Catheter Ablation for AF: ALONE-AF Trial
Discontinuation of Anticoagulation After Catheter Ablation for AF: OCEAN Trial
Pre, Intra, and Post-Procedural Imaging for LAA Closure - Role of TEE, ICE, & CT
New Technologies for Left Atrial Appendage Closure
Panel and Audience Discussion (25 minutes) - All Faculty
4:30 – 5:00 PM Break
5:00 – 6:30 PM
Late Breaking Clinical Science Session I
All talks 7 minutes & 3 minutes Q&A
6:30 PM ADJOURN
7:00-9:00 PM
Reception for All Attendees, Faculty, and Industry
Location: Pre-Function Area Level 2, Outside Exhibit Hall
Omni Seaport Hotel Boston
450 Summer Street, Boston, MA
FRIDAY, FEBRUARY 6, 2026
7:00-7:30 AM Welcome and Introduction
7:30-8:30 AM
Biophysics of Pulsed Field Ablation for Atrial Fibrillation – Implications for Safety and Efficacy
Supported by an Educational Grant from Johnson & Johnson MedTech
All lectures 7 minutes. Q&A, Panel Discussion 25 minutes.
Biophysics and Thermal Effects of Pulsed Field Ablation
Effect of Electrode Irrigation on Brain MRI Findings with Pulsed Field Ablation
Impact of Lesion Delivery and Irrigation Rates on Neurovascular Events with PFA for AF
Real-Time Prediction of Irreversible Lesion Size using a Novel PFA Index
Maximizing Lesion Depth Using High Voltage PFA Waveform
Panel and Audience Discussion (25 minutes) – All Faculty
8:30-9:30 AM
Case Transmissions Session 3
9:30-10:00 AM Break
10:00 AM-12:30 PM
Case Transmissions Session 4
12:30-1:30 PM Lunch
1:30-2:30 PM
Beyond Pulmonary Vein Isolation: How to Maximize Efficacy
Supported by an Educational Grant from Medtronic
All lectures 7 minutes. Panel Discussion 25 minutes.
Have We Achieved Optimal Durability of Pulmonary Vein Isolation?
Pulsed Field Ablation for Redo Procedures in Patients with Persistent AF
Anatomic Approaches to Adjunctive Ablation for Persistent AF: SPHERE & ADVANTAGE-AF
Long-Term Durability of Linear Lesions with Pulsed Field Ablation
Anatomical vs Targeted Ablation - Role of AF Mapping
Panel and Audience Discussion - All Faculty
FRIDAY CONTINUES >>>
FRIDAY CONTINUED
2:30-3:30 PM
Endpoints and Outcomes of Catheter Ablation for Atrial Fibrillation
All lectures 7 minutes. Panel Discussion 25 minutes.
Long-Term Outcomes of Catheter Ablation for AF in Patients with Heart Failure
Burden and Frequency of AF Recurrences after AF Ablation - Insights from Implantable Monitoring
Optimal Blanking Period After Pulsed Field Ablation for Atrial Fibrillation
Autonomic Modulation to Improve AF Ablation Outcomes
Atrial Fibrillation Mapping - Impact on Ablation Outcomes
Panel and Audience Discussion (25 minutes): All Faculty
3:30-4:00 PM Break
4:00-5:30 PM
Case Transmissions Session 5
5:30-7:00 PM
Late Breaking Clinical Science Session II and Best Abstract Award
All talks 7 minutes & 3 minutes Q&A
7:00 PM ADJOURN
SATURDAY, FEBRUARY 7, 2026
7:00-7:30 AM Welcome and Introduction
7:30 AM-9:30 AM
Case Transmissions Session 6
9:30-10 AM: Break
10:00-11:00 AM
Pulsed Field Ablation – Safety I
All lectures 7 minutes. Panel Discussion 25 minutes.
Complications Associated with Pulsed Field vs Radiofrequency Ablation for AF
Collateral Injury with Pulsed Field Ablation for Atrial Fibrillation
MANIFEST-US - Real-World Safety of Pulsed Field Ablation in 40,000 Patients
Generalized Coronary Artery Spasm (Early and Late) after Pulsed Field Ablation
HRS Pulsed Field Ablation Registry
Panel and Audience Discussion (25 minutes) – All Faculty
11:00 AM-12:00 PM
Pulsed Field Ablation - Safety II
Supported by an Educational Grant from Abbott
All lectures 7 minutes. Panel Discussion 25 minutes.
Minimizing Adverse Events from Air Embolization with Large Bore PFA Sheaths
Prevalence and Mitigation of PFA Related Phrenic Nerve Stunning
Conscious Sedation for PFA Procedures - Waveform Optimization to Minimize MS Stimulation
Predicting PFA Lesions Using the E-Field Approach - Implications for Efficacy and Safety
ICE integrated PFA Workflows Using AI-Based Model Segmentation - Minimizing Radiation Exposure
Panel and Audience Discussion (25 minutes) – All Faculty
12:00-12:30 PM Working Lunch
12:30-3:00 PM
Case Transmissions Session 7
3:00-4:00 PM
Challenging Cases in AF Management and Stroke Prevention
(7-minute presentation & 5-minute discussion for each case)
4:00 ADJOURN
5:00 - 9:00 PM FELLOWS PROGRAM