31st Annual International AF Symposium™
Preliminary Scientific Program 2026

This intensive three-day symposium brings together the world's leading medical scientists to share the most recent advances
in the field of atrial fibrillation in a highly interactive environment.

THURSDAY, FEBRUARY 5, 2026

7:00-7:30 AM Welcome and Introduction

7:30-8:30 AM
New Trends in Prediction and Risk Factor Modification for AF
Moderators: Mina Chung, MD and Nassir Marrouche, MD
All lectures 7 minutes. Panel and Audience Discussion 25 minutes.

Predicting Risk for Atrial Fibrillation in the Era of Artificial Intelligence
Shaan Khurshid, MD, MPH

Impact of Diet on Risk of AF and AF Ablation Outcomes
Christine Albert, MD

Role of GLP-1 RA on AF and AF Ablation Outcomes
Gianluca Iacobellis, MD, PhD

Current Status and Future Role of Genetics in the Management of AF
Patrick Ellinor, MD, PhD

Integrating Wearables into Clinical Trials and Electrophysiology Practice
Jason Andrade, MD

Panel and Audience Discussion (25 minutes)

8:30-9:30 AM
Spotlight Session – New and Emerging Technologies in EP
Moderator: Paul Wang, MD
All lectures 5 minutes.

Image-Guided Cardioneuroablation Planning Using ADAS 3D
Giulio Falasconi, MD

Coherent Sine Burst Electroportaion (CSE) Ablation System US IDE Study for Patients with Atrial Fibrillation
Ante Anic, MD

First Clinical Experience with HOTWIRE: A Sheath Agnostic Transseptal Access System Featuring an Intelligent Impedance-Sensing Algorithm
Devi Nair, MD

PFAnalyzer: Electrogram-guided Pulsed Field Ablation
Ante Anic, MD

CONFORM Trial Update featuring AcuFORM Experience
Shepal Doshi, MD

Non-invasive Global Mapping to Guide Personalized AF Therapy and Catheter Ablation
Till Althoff, MD

Real-Time Tissue Assessment in Stunned Myocardium to Predict Recurrence
Tim Maher, MD

A Practical Guide to AI in EP Remote Monitoring: Workflows, Evidence, and Impact
Babak Bozorgnia MD

Non-Invasive Mapping of AF Drivers to Guide Comprehensive Ablation Strategies
Sei Iwai, MD 

The RESTART Trial: Advancing Care for Patients with Isolated Veins
John Hummel, MD

FDA Presentation: Update on the Regulatory Process for New Devices for AF Ablation and LAA Closure
Aneesh Deoras, MSE

9:30-10:00 AM Break

10 AM-12:30 PM
Case Transmissions Session 1
Moderator: Moussa Mansour, MD

12:30-1:30 PM Lunch

1:30-2:30 PM
Case Transmissions Session 2
Moderator: Moussa Mansour, MD

2:30-3:30 PM
Stroke Risk Management in Atrial Fibrillation Session I
Moderators: John Day, MD and Andrea Russo, MD
All lectures 7 minutes. Panel and Audience Discussion 25 minutes.

Factor XI and XIa Inhibition for Stroke Prevention in AF: OCEANIC-AF, AZALEA, and Other Studies
Marc Sabatine, MD, MPH

Management of Device-Detected AF: Will ARTESIA and NOAH-AFNET 6 Change Current Guidelines?
Rod Passman, MD

LAA Closure in Patients with Prior Hemorrhagic or Anticoagulant-Resistant Ischemic Strokes - Update from Clinical Trials and Registries
James Freeman, MD, MPH

LAA Closure Compared to Medical Therapy in Patients with AF (CLOSURE-AF Trial)
Thorsten Lewalter, MD

Optimal Anticoagulation and Follow-up Strategies after LAA Closure
Jonathan Hsu, MD

Panel and Audience Discussion (25 minutes) – All Faculty

THURSDAY CONTINUES >>>

THURSDAY CONTINUED

3:30-4:30 PM
Stroke Risk Management in Atrial Fibrillation Session II
Supported by an Educational Grant from Boston Scientific
Moderators: Christopher Ellis, MD and Kevin Heist, MD
All lectures 7 minutes. Panel and Audience Discussion 25 minutes.

Patient Selection for Concomitant PVI and LAA Closure - Applying OPTION to Clinical Practice
Devi Nair, MD

Discontinuation of Anticoagulation After Catheter Ablation for AF: ALONE-AF Trial
Boyoung Joung, MD

Discontinuation of Anticoagulation After Catheter Ablation for AF: OCEAN Trial
Atul Verma, MD

Pre, Intra, and Post-Procedural Imaging for LAA Closure - Role of TEE, ICE, & CT
Shephal Doshi, MD

New Technologies for Left Atrial Appendage Closure
Vivek Reddy, MD

Panel and Audience Discussion (25 minutes) - All Faculty

4:30 – 5:00 PM Break

5:00 – 7:00 PM
Late Breaking Clinical Science Session I
Moderators: Kalyanam Shivkumar, MD, PhD and Luigi Di Biase, MD, PhD
All talks 7 minutes & 3 minutes Q&A

7:00 PM ADJOURN

7:00-9:00 PM
Reception for All Attendees, Faculty, and Industry
Location: Pre-Function Area Level 2, Outside Exhibit Hall
Omni Seaport Hotel Boston
450 Summer Street, Boston, MA

FRIDAY, FEBRUARY 6, 2026

7:00-7:30 AM Welcome and Introduction

7:30-8:30 AM
Biophysics of Pulsed Field Ablation for Atrial Fibrillation – Implications for Safety and Efficacy
Supported by an Educational Grant from Johnson & Johnson MedTech
Moderators: Luigi Di Biase, MD, PhD and Tina Baykaner, MD
All lectures 7 minutes. Q&A, Panel Discussion 25 minutes.

Biophysics and Thermal Effects of Pulsed Field Ablation
Damijan Miklavcic, DSc

Effect of Electrode Irrigation on Brain MRI Findings with Pulsed Field Ablation
Shiro Nakahara, MD

Impact of Lesion Delivery and Irrigation Rates on Neurovascular Events with PFA for AF
Andrea Natale, MD

Real-Time Prediction of Irreversible Lesion Size using a Novel PFA Index
Hiroshi Nakagawa, MD, PhD

Maximizing Lesion Depth Using High Voltage PFA Waveform
Kenneth Ellenbogen, MD

Panel and Audience Discussion (25 minutes) – All Faculty

8:30-9:30 AM
Case Transmissions Session 3
Moderator: Moussa Mansour, MD

9:30-10:00 AM Break

10:00 AM-12:30 PM
Case Transmissions Session 4
Moderator: Moussa Mansour, MD

12:30-1:30 PM Lunch

1:30-2:30 PM
Beyond Pulmonary Vein Isolation: How to Maximize Efficacy
Supported by an Educational Grant from Medtronic
Moderators: Pierre Jais, MD and Andrea Sarkozy, MD, PhD
All lectures 7 minutes. Panel Discussion 25 minutes.

Have We Achieved Optimal Durability of Pulmonary Vein Isolation?
Jacob Koruth, MD

Pulsed Field Ablation for Redo Procedures in Patients with Persistent AF
Andrea Sarkozy, MD, PhD

Anatomic Approaches to Adjunctive Ablation for Persistent AF: SPHERE & ADVANTAGE-AF
Moussa Mansour, MD

Long-Term Durability of Linear Lesions with Pulsed Field Ablation
Andrea Natale, MD

Anatomical vs Targeted Ablation - Role of AF Mapping
Jonathan Piccini, MD

Panel and Audience Discussion - All Faculty

FRIDAY CONTINUES >>>

FRIDAY CONTINUED

2:30-3:30 PM
Endpoints and Outcomes of Catheter Ablation for Atrial Fibrillation
Moderators: Meleze Hocini, MD and Claudio Tondo, MD, PhD
All lectures 7 minutes. Panel Discussion 25 minutes.

Long-Term Outcomes of Catheter Ablation for AF in Patients with Heart Failure
Nassir Marrouche, MD

Burden and Frequency of AF Recurrences after AF Ablation - Insights from Implantable Monitoring
Vivek Reddy, MD

Optimal Blanking Period After Pulsed Field Ablation for Atrial Fibrillation
Luigi Di Biase, MD, PhD

Autonomic Modulation to Improve AF Ablation Outcomes
William Whang, MD

Atrial Fibrillation Mapping - Impact on Ablation Outcomes
Pierre Jais, MD

Panel and Audience Discussion (25 minutes): All Faculty

3:30-4:00 PM Break

4:00-5:30 PM
Case Transmissions Session 5
Moderator: Moussa Mansour, MD

5:30-7:00 PM
Late Breaking Clinical Science Session II and Best Abstract Award
All talks 7 minutes & 3 minutes Q&A

7:00 PM ADJOURN

SATURDAY, FEBRUARY 7, 2026

7:00-7:30 AM Welcome and Introduction

7:30 AM-9:30 AM
Case Transmissions Session 6
Moderator: Moussa Mansour, MD

9:30-10 AM: Break

10:00-11:00 AM
Pulsed Field Ablation – Safety I
Moderators: Edward Gerstenfeld, MD and Isabel Deisenhofer, MD
All lectures 7 minutes. Panel Discussion 25 minutes.

Complications Associated with Pulsed Field vs Radiofrequency Ablation for AF
Hugh Calkins, MD

Collateral Injury with Pulsed Field Ablation for Atrial Fibrillation
Dhanunjaya Lakkireddy, MD

MANIFEST-US - Real-World Safety of Pulsed Field Ablation in 40,000 Patients
Vivek Reddy, MD

Generalized Coronary Artery Spasm (Early and Late) after Pulsed Field Ablation
Melanie Gunawardene, MD

HRS Pulsed Field Ablation Registry
Mina Chung, MD

Panel and Audience Discussion (25 minutes) – All Faculty

11:00 AM-12:00 PM
Pulsed Field Ablation - Safety II
Supported by an Educational Grant from Abbott
Moderators: Atul Verma, MD and David DeLurgio, MD
All lectures 7 minutes. Panel Discussion 25 minutes.

Minimizing Adverse Events from Air Embolization with Large Bore PFA Sheaths
Larry Chinitz, MD

Prevalence and Mitigation of PFA Related Phrenic Nerve Stunning
Boris Schmidt, MD

Conscious Sedation for PFA Procedures - Waveform Optimization to Minimize MS Stimulation
Roland Tilz, MD

Predicting PFA Lesions Using the E-Field Approach - Implications for Efficacy and Safety
Melanie Gunawardene, MD

ICE integrated PFA Workflows Using AI-Based Model Segmentation - Minimizing Radiation Exposure
Devi Nair, MD

Panel and Audience Discussion (25 minutes) – All Faculty

12:00-12:30 PM Working Lunch

12:30-3:00 PM
Case Transmissions Session 7and 8
Moderator: Moussa Mansour, MD

3:00-4:00 PM
Challenging Cases in AF Management and Stroke Prevention
(7-minute presentation & 5-minute discussion for each case)
Moderator: David Keane, MD, PhD
Faculty: Francis Marchlinski, MD, John Day, MD, Laurent Macle, MD, Edward Gerstenfeld, MD, Sana Al Khatib, MD & Young-Hoon Kim, MD, PhD

4:00 ADJOURN

5:00 - 9:00 PM FELLOWS PROGRAM

CASE TRANSMISSIONS TO BE FEATURED IN SESSIONS 1-8

Concomitant PVI and Watchman LAA Closure Using Novel 4-D Siemens ICE Catheter
Devi Nair, MD (St. Bernards Healthcare, Jonesboro, AR)

Concomitant PVI and Watchman LAA Closure
Dingxin Qin, MD, William Hucker, MD and Kevin Heist, MD (Massachusetts General Hospital, Boston, MA)

AF Ablation Using the Farawave PFA Catheter with Prior Watchman LAA Closure
Frank Cuoco, MD (Charleston Heart Specialists - Charleston, SC)

Redo Ablation Using Farawave and Focal PFA Catheters
Moussa Mansour, MD (Massachusetts General Hospital, Boston, MA)

Cavotricuspid Isthmus Ablation Using Farawave PFA Catheter
TBD

AF Ablation Using Faraflex Large Footprint Focal PFA Catheter
Andrea Natale, MD (Texas Cardiac Arrhythmia Institute, Austin, TX)

AF Ablation Guided by Cortex Mapping System
Shephal Doshi, MD (Pacific Heart Institute, Santa Monica, CA)

PVI and Posterior Wall Ablation Using Farawave Contact Sensing Catheter
Rodney Horton, MD (Texas Cardiac Arrhythmia Institute, Austin, TX)

PVI Using Varipulse PFA Catheter and Sound Star Crystal ICE
Christopher Porterfield, MD, PhD, MPH (Aurora Denver Cardiology Associates - Aurora, CO)

PVI and Posterior Wall Ablation Using Varipulse PFA Catheter and ICE
Tom De Potter, MD (OLV Hospital, Aalst, Belgium)

AF Ablation Using Omnypulse Large Footprint Focal PFA Catheter
TBD

PVI and CTI Ablation Using Dual Energy STSF Focal Catheter
Benjamin Berte, MD (Hirslanden St Anna Hospital Lucerne)

Concomitant PVI and LAA Closure Using Nuvision 4-D ICE
Omar Kreidieh, MD and Nassir Marrouche, MD (Tulane, New Orleans, Louisiana)

Electroanatomic Mapping Using Mulltielectrode FEATHER Catheter
Mattias Duytschaever, MD (St. Jan University, Brugge-Oostende Belgium)

Ablation of Persistent Atrial Fibrillation Using the SPHERE 9 Lattice Tip PFA Catheter
Amin Al-Ahmad, MD (Texas Cardiac Arrhythmia Institute, Austin, TX)

Redo Ablation of Atrial Fibrillation Using the SPHERE 9 Lattice Tip PFA Catheter
Miguel Valderrabano, MD (Houston Methodist Hospital)

PVI Using the SPHERE 360 Large Lattice Tip PFA Catheter
Petr Peichl, MD (IKEM, Prague, Czech Republic)

PVI Using the SPHERE 360 Large Lattice Tip PFA Catheter
Devi Nair, MD (St. Bernards Healthcare, Jonesboro, AR)

Pulmonary Vein Isolation Using the PulseSelect Contact Sensing Catheter
Atul Verma, MD (Southlake Regional Health Centre, Toronto, Canada)

AF Ablation Using the Balloon in Basket Volt PFA System
Roderick Tung, MD and Wilber Su, MD (University of Arizona College of Medicine, Phoenix, AZ)

AF Ablation Using the Balloon in Basket Volt PFA System with Comcomitant Amulet LAA Closure
Boris Schmidt, MD (Centrum Bethanien, Frankfort, Germany)

Persistent AF Ablation with High Density Mapping and Dual Energy TactiFlex Duo Ablation Catheter
Isabel Deisenhofer, MD, Sarah Lengauer, MD and Mohammad Al Fayad, MD (German Heart Center Munich)

Concomitant Pulmonary Vein Isolation and Amulet LAA Closure
Devi Nair, MD (St. Bernards Healthcare Jonesboro, AR)

AF Ablation Guided by the VERAFEYE 2D/4D Cardiac Visualization System
Ante Anic, MD (University Clinical Hospital, Split, Croatia)

PVI, HD Mapping, and Linear Ablation with the Globe 122-Electrode Spherical Array
Devi Nair, MD (St. Bernards Healthcare, Jonesboro, AR)

Beyond PVI: CTI and Mitral Isthmus Ablation with a Programmable 122 Electrode Spherical Array
Vivek Reddy, MD (Mount Sinai Medical Center, New York, NY)

AF Ablation Using High Voltage Field Medical PFA Catheter
Devi Nair, MD (St. Bernards Healthcare, Jonesboro, AR)

AF Ablation Using Nanosecond Pulse Bioscience PFA Catheter
Vivek Reddy, MD & Petr Neuzil, MD, PhD (Na Homolce Hospital, Prague, Czech Republic)

AF Activation Driver Mapping and Ablation Guided by the STAR Apollo AI-Assisted and EnSite Mapping Systems
Matthew McKillop, MD and Aaditya Vora, MD (Baptist Health, Jacksonville, FL)

Catheter-Based Endocardial LAA Elimination with the APPEND System
Vivek Reddy, MD (Mount Sinai Medical Center, New York, NY)